Journal article

Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy

WD Rawlinson, SB Boppana, KB Fowler, DW Kimberlin, T Lazzarotto, S Alain, K Daly, S Doutré, L Gibson, ML Giles, J Greenlee, ST Hamilton, GJ Harrison, L Hui, CA Jones, P Palasanthiran, MR Schleiss, AW Shand, WJ van Zuylen

Lancet Infectious Diseases | Published : 2017

Abstract

Congenital cytomegalovirus is the most frequent, yet under-recognised, infectious cause of newborn malformation in developed countries. Despite its clinical and public health importance, questions remain regarding the best diagnostic methods for identifying maternal and neonatal infection, and regarding optimal prevention and therapeutic strategies for infected mothers and neonates. The absence of guidelines impairs global efforts to decrease the effect of congenital cytomegalovirus. Data in the literature suggest that congenital cytomegalovirus infection remains a research priority, but data are yet to be translated into clinical practice. An informal International Congenital Cytomegaloviru..

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Funding Acknowledgements

The authors thank Rajiv Khanna (QIMR Berghofer Medical Research Institute, Brisbane, Australia) for support, and Michael Cannon (Centers for Disease Control and Prevention, Atlanta, USA) for comments on the manuscript. Funding of the congenital cytomegalovirus consensus meeting was provided by the organisation of the 5th International Congenital Cytomegalovirus Conference and 15th International Cytomegalovirus/Betaherpesvirus Workshop. Independent, unrestricted educational grants were provided by Abbott, CSL, DiaSorin, and Roche. These companies did not contribute in any way to the development of the consensus recommendations, or to the development, content, or review of the manuscript containing these recommendations.